Epilepsia: Volumen 61, Issue 6, Junio 2020
Seizures in autoimmune encephalitis: Kindling the fire
Robb Wesselingh Helmut Butzkueven Katherine Buzzard David Tarlinton Terence J. O'Brien Mastura Monif
Pages: 1033-1044
The postictal state — What do we know?
Julia C. M. Pottkämper Jeannette Hofmeijer Jeroen A. van Waarde Michel J. A. M. van Putten
Pages: 1045-1061
Physical activity in people with epilepsy: A systematic review
Emma C. Johnson J. Helen Cross Colin Reilly
Pages: 1062-1081
Does cannabidiol have antiseizure activity independent of its interactions with clobazam? An appraisal of the evidence from randomized controlled trials
Meir Bialer Emilio Perucca
Pages: 1082-1089
Cannabidiol efficacy and clobazam status: A systematic review and meta‐analysis
Simona Lattanzi | Eugen Trinka | Pasquale Striano | Gaetano Zaccara | Cinzia Del Giovane | Raffaele Nardone | Mauro Silvestrini | Francesco Brigo
Pages: 1090-1098
Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open‐label safety study
Michael R. Sperling Pavel Klein Sami Aboumatar Michael Gelfand Jonathan J. Halford Gregory L. Krauss William E. Rosenfeld David G. Vossler Robert Wechsler Leona Borchert Marc Kamin
Pages: 1099-1108
Effectiveness and safety of perampanel monotherapy for focal and generalized tonic‐clonic seizures: Experience from a national multicenter registry
Rafael Toledano Delgado Irene García‐Morales Beatriz Parejo‐Carbonell Adolfo Jiménez‐Huete David Herrera‐Ramirez Ayoze González‐Hernández Fernando Ayuga Loro Estevo Santamarina Amat Pages: 1109-1119
Usefulness of saliva for perampanel therapeutic drug monitoring
Do‐Yong Kim Jangsup Moon Yong‐Won Shin Soon‐Tae Lee Keun‐Hwa Jung Kyung‐Il Park Ki‐Young Jung Manho Kim SeungHwan Lee Kyung‐Sang Yu In‐Jin Jang KaHeon Song Kon Chu Sangkun Lee
Pages: 1120-1128
Program of Active Consumer Engagement in Self‐Management in Epilepsy: Replication and extension of a self‐management randomized controlled trial
Erica K. Johnson Robert T. Fraser Steven Lashley Jason Barber Erica M. Brandling‐Bennett David G. Vossler John W. Miller Lisa Caylor Tessala Warheit‐Niemi
Pages: 1129-1141
Lessons learned from 40 novel PIGA patients and a review of the literature
Allan Bayat Alexej Knaus Manuela Pendziwiat Alexandra Afenjar Tahsin Stefan Barakat Friedrich Bosch Bert Callewaert Patrick Calvas Berten Ceulemans Nicolas Chassaing Christel Depienne Milda Endziniene Carlos R. Ferreira Carolina Fischinger Moura de Souza Cécile Freihuber Shiva Ganesan Pages: 1142-1155
Trait and state interoceptive abnormalities are associated with dissociation and seizure frequency in patients with functional seizures
Akihiro Koreki Sarah N. Garfkinel Marco Mula Niruj Agrawal Sarah Cope Talia Eilon Cassandra Gould Van Praag Hugo D. Critchley Mark Edwards Mahinda Yogarajah
Pages: 1156-1165
Severe psychological distress among patients with epilepsy during the COVID‐19 outbreak in southwest China
Xiaoting Hao Dong Zhou Zhe Li Guojun Zeng Nanya Hao Enzhi Li Wenjing Li Aiping Deng Mintao Lin Bo Yan
Pages: 1166-1173
High‐frequency electrical stimulation of the anterior thalamic nuclei increases vigilance in epilepsy patients during relaxed and drowsy wakefulness
Iancu Bucurenciu Anke Maren Staack Alireza Gharabaghi Bernhard J. Steinhoff
Pages: 1174-1182
Stereotactic Laser Ablation for Mesial Temporal Lobe Epilepsy: A prospective, multicenter, single‐arm study
Michael R. Sperling Robert E. Gross Guy E. Alvarez Guy M. McKhann Vicenta Salanova Julie Gilmore
Pages: 1183-1189
Stereotactic laser anterior corpus callosotomy for Lennox‐Gastaut syndrome
James X. Tao David Satzer Naoum P. Issa John Collins Shasha Wu Sandra Rose Julia Henry Fabiane Santos de Lima Douglas Nordli Peter C. Warnke
Pages: 1190-1200
Psychosocial profiles and their predictors in epilepsy using patient‐reported outcomes and machine learning
Colin B. Josephson Jordan D. T. Engbers Meng Wang Kevin Perera Pamela Roach Tolulope T. Sajobi Samuel Wiebe Calgary Comprehensive Epilepsy Program collaborators
Pages: 1201-1210
Cognitive phenotypes in temporal lobe epilepsy utilizing data‐ and clinically driven approaches: Moving toward a new taxonomy
Anny Reyes Erik Kaestner Lisa Ferguson Jana E. Jones Michael Seidenberg William B. Barr Robyn M. Busch Bruce P. Hermann Carrie R. McDonald
Pages: 1211-1220
Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome
Sara Larivière Yifei Weng Reinder Vos de Wael Jessica Royer Birgit Frauscher Zhengge Wang Andrea Bernasconi Neda Bernasconi Dewi V. Schrader Zhiqiang Zhang Boris C. Bernhardt
Pages: 1221-1233
Utility of genetic testing for therapeutic decision‐making in adults with epilepsy
Katrine M. Johannesen Natalya Nikanorova Dragan Marjanovic Agnieszka Pavbro Line H. G. Larsen Guido Rubboli Rikke S. Møller
Pages: 1234-1239
pCREB expression in human tissues from epilepsy surgery
Dalia De Santis Laura Rossini Laura Tassi Giuseppe Didato Giovanni Tringali Massimo Cossu Manuela Bramerio Francesco Padelli Maria Cristina Regondi Francesca Colciaghi Eleonora Aronica Roberto Spreafico Rita Garbelli
Pages: 1240-1252
Seizure‐related apneas have an inconsistent linkage to amygdala seizure spread
Katherine Park Kiran Kanth Sami Bajwa Fady Girgis Kiarash Shahlaie Masud Seyal
Pages: 1253-1260
Use of ketogenic diet therapy in infants with epilepsy: A systematic review and meta‐analysis
Laura Lyons Natasha E. Schoeler Dean Langan J. Helen Cross
Pages: 1261-1281
Neonatal vitamin D status and risk of childhood epilepsy
Ina O. Specht Fanney Thorsteinsdottir Karen Christina Walker Jørn Olsen Berit L Heitmann
Pages: 1282-1290
A rat model of valproate teratogenicity from chronic oral treatment during pregnancy
Dana Jazayeri Emma Braine Stuart McDonald Sebastian Dworkin Kim L. Powell Karen Griggs Frank J. E. Vajda Terence J. O’Brien Nigel C. Jones
Pages: 1291-1300
Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats
Kyle E. Thomson Cameron S. Metcalf Thomas G. Newell Jennifer Huff Sharon F. Edwards Peter J. West Karen S. Wilcox
Pages: 1301-1311
New onset acute symptomatic seizure and risk factors in coronavirus disease 2019: A retrospective multicenter study
Lu Lu Weixi Xiong Dan Liu Jing Liu Dan Yang Nian Li Jie Mu Jian Guo Weimin Li Gang Wang Hui Gao Yingying Zhang Mintao Lin Lei Chen Sisi Shen Hesheng Zhang Josemir W. Sander Jianfei Luo Shengli Chen Dong Zhou
Pages: e49-e53
Characterization of organophosphate‐induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure
Julie Enderlin Alexandre Igert Stéphane Auvin Florian Nachon Grégory Dal Bo Nina Dupuis
Pages: e54-e59
Electrocorticographic and neurochemical findings after local cortical valproate application in patients with pharmacoresistant focal epilepsy
Dirk‐Matthias Altenmüller Jonas M. Hebel Cagan Deniz Silvanie Volz Josef Zentner Thomas J. Feuerstein Andreas Moser
Pages: e60-e65
The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus
Abhishek G. Sathe Jordan J. Elm James C. Cloyd James M. Chamberlain Robert Silbergleit Jaideep Kapur Hannah R. Cock Nathan B. Fountain Shlomo Shinnar Daniel H. Lowenstein Robin A. Conwit Thomas P. Bleck Lisa D. Coles
Pages: e66-e70
Epilepsia: Volumen 61, Issue 5, Mayo 2020
How technology is driving the landscape of epilepsy surgery
Christian Dorfer Bertil Rydenhag Gordon Baltuch Vivek Buch Jeffrey Blount Robert Bollo Jason Gerrard Daniel Nilsson Karl Roessler James Rutka Ashwini Sharan Dennis Spencer Arthur Cukiert
Pages: 841-855
Ictal onset sites and γ‐aminobutyric acidergic neuron loss in epileptic pilocarpine‐treated rats
Megan Wyeth Monica Nagendran Paul S. Buckmaster
Pages: 856-867
A knock‐in mouse model for KCNQ2‐related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment
Mathieu Milh Pierre Roubertoux Najoua Biba Julie Chavany Adeline Spiga Ghata Camille Fulachier Stephan Christopher Collins Christel Wagner Jean‐Christophe Roux Binnaz Yalcin Marie‐Solenne Félix Florence Molinari Pierre‐Pascal Lenck‐Santini Laurent Villard
Pages: 868-878
Early developmental electroencephalography abnormalities, neonatal seizures, and induced spasms in a mouse model of tuberous sclerosis complex
Nicholas Rensing Kevin J. Johnson Thomas J. Foutz Joseph L. Friedman Rafael Galindo Michael Wong
Pages: 879-891
Developmental decrease in parvalbumin‐positive neurons precedes increase in flurothyl‐induced seizure susceptibility in the Brd2 +/− mouse model of juvenile myoclonic epilepsy
Emily McCarthy Faariah Shakil Patrick Saint Ange Emily Morris Cameron James Miller Shilpa Pathak David A. Greenberg Jana Velíšková Libor Velíšek
Pages: 892-902
Deep brain stimulation reduces evoked potentials with a dual time course in freely moving rats: Potential neurophysiological basis for intermittent as an alternative to continuous stimulation
Mathieu Sprengers Robrecht Raedt Lars Emil Larsen Jean Delbeke Wytse Jan Wadman Paul Boon Kristl Vonck
Pages: 903-913
Functional characterization of the antiepileptic drug candidate, padsevonil, on GABAA receptors
Isabelle Niespodziany Philippe Ghisdal Brice Mullier Martyn Wood Laurent Provins Rafal M. Kaminski Christian Wolff
Pages: 914-923
Late drug‐resistance in mild MTLE: Can it be influenced by preexisting white matter alterations?
Angelo Labate Maria Eugenia Caligiuri Francesco Fortunato Edoardo Ferlazzo Umberto Aguglia Antonio Gambardella
Pages: 924-934
Pharmacokinetics and safety of VALTOCO (NRL‐1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri‐ictal) and nonseizure (interictal) conditions: A phase 1, open‐label study
Robert Edward Hogan Daniel Tarquinio Michael R. Sperling Pavel Klein Ian Miller Eric B. Segal Adrian L. Rabinowicz Enrique Carrazana
Pages: 935-943
Pregnancy after valproate withdrawal—Fetal malformations and seizure control
Frank J. E. Vajda Terence J. O’Brien Janet E. Graham Alison A. Hitchcock Cecilie M. Lander Mervyn J. Eadie
Pages: 944-950
Digital conversations about suicide among teenagers and adults with epilepsy: A big‐data, machine learning analysis
Tatiana Falcone Anjali Dagar Ruby C. Castilla-Puentes Amit Anand Caroline Brethenoux Liliana G. Valleta Patrick Furey Jane Timmons-Mitchell Elia Pestana-Knight
Pages: 951-958
Circulating miR‐146a and miR‐134 in predicting drug‐resistant epilepsy in patients with focal impaired awareness seizures
Maria Leontariti Margaritis Avgeris Martha‐Spyridoula Katsarou Nikolaos Drakoulis Anna Siatouni Anastasia Verentzioti Athanasia Alexoudi Aggeliki Fytraki Panayiotis Patrikelis Dido Vassilacopoulou Pages: 959-970
Epilepsy in LAMA2‐related muscular dystrophy: An electro‐clinico‐radiological characterization
Daniel Natera‐de Benito Jordi Muchart Debora Itzep Carlos Ortez Lidia González‐Quereda Pía Gallano Alia Ramirez Javier Aparicio Jana Domínguez‐Carral Laura Carrera‐García Jessica Expósito‐Escudero Nathalia Pardo Cardozo Daniel Cuadras Anna Codina Cristina Jou Cecilia Jimenez‐Mallebrera Francesc Palau Jaume Colomer Alexis Arzimanoglou Andrés Nascimento Victoria San Antonio‐Arce
Pages: 971-983
Semiologic subgroups of insulo‐opercular seizures based on connectional architecture atlas
Haixiang Wang Aileen McGonigal Kai Zhang Qiang Guo Bingqing Zhang Xiu Wang Xiao Wang Jiuluan Lin Xiancheng Song Qian Feng Siyu Wang Mengyang Wang Xiaoqiu Shao Xiaoyan Liu Liang Wang Wenjing Zhou
Pages: 984-994
Phenotypic and genetic spectrum of epilepsy with myoclonic atonic seizures
Shan Tang Laura Addis Anna Smith Simon D. Topp Manuela Pendziwiat Davide Mei Alasdair Parker Shakti Agrawal Elaine Hughes Karine Lascelles Ruth E. Williams Penny Fallon Robert Robinson Helen J. Cross Tammy Hedderly Christin Eltze Tim Kerr Archana Desurkar Nahin Hussain Maria Kinali Irene Bagnasco Grace Vassallo William Whitehouse Sushma Goyal Michael Absoud EuroEPINOMICS‐RES Consortium Rikke S. Møller Ingo Helbig Yvonne G. Weber Carla Marini Renzo Guerrini Michael A. Simpson Deb K. Pal
Pages: 995-1007
Interactions between in vivo neuronal‐glial markers, side of hippocampal sclerosis, and pharmacoresponse in temporal lobe epilepsy
Luciana R. Pimentel‐Silva Raphael F. Casseb Mônica M. Cordeiro Bruno A. G. Campos Marina K. M. Alvim Fábio Rogerio Clarissa L. Yasuda Fernando Cendes
Pages: 1008-1018
Quantitative analysis of hyperkinetic seizures and correlation with seizure onset zone
Julie Fayerstein Aileen McGonigal Francesca Pizzo Francesca Bonini Stanislas Lagarde Aurore Braquet Agnès Trébuchon Romain Carron Didier Scavarda Scholly Julia Isabelle Lambert Bernard Giusiano Fabrice Bartolomei
Pages: 1019-1026
Upregulation of lactate dehydrogenase A in a chronic model of temporal lobe epilepsy
Nagisa Sada Shogo Suto Mana Suzuki Shoichiro Usui Tsuyoshi Inoue
Pages: e37-e42
Influence of dose and antiepileptic comedication on brivaracetam serum concentrations in patients with epilepsy
Anne Hagemann Dennis Klimpel Christian G. Bien Christian Brandt Theodor W. May
Pages: e43-e48
Epilepsia: Volumen 61, Issue 4, Abril 2020
Understanding the challenge of comparative effectiveness research in focal epilepsy: A review of network meta‐analyses and real‐world evidence on antiepileptic drugs
Solène Thieffry Pavel Klein Michel Baulac Jonathan Plumb Barbara Pelgrims Sara Steeves Simon Borghs
Pages: 595-609
Analysis of antiseizure drug‐related adverse reactions from the electronic health record using the common data model
Sun Ah Choi Hunmin Kim Seok Kim Sooyoung Yoo Soyoung Yi Yonghoon Jeon Hee Hwang Ki Joong Kim
Pages: 610-616
Pregabalin adjunctive therapy for focal onset seizures in children 1 month to <4 years of age: A double‐blind, placebo‐controlled, video‐electroencephalographic trial
Donald Mann Jeremias Antinew Lloyd Knapp Mary Almas Jing Liu Joseph Scavone Ruoyong Yang Margaret Modequillo Iryna Makedonska Marilyn Ortiz Alla Kyrychenko Douglas Nordli Viktor Farkas Mark Kristof Farkas on behalf of the A0081042 study group
Pages: 617-626
A retrospective comparison of phenobarbital and levetiracetam for the treatment of seizures following cardiac surgery in neonates
Céline Thibault Maryam Y. Naim Nicholas S. Abend Daniel J. Licht J. William Gaynor Rui Xiao Shavonne L. Massey
Pages: 627-635
Long‐term safety, efficacy, and quality of life outcomes with adjunctive brivaracetam treatment at individualized doses in patients with epilepsy: An up to 11‐year, open‐label, follow‐up trial
Terence J. O’Brien Simon Borghs Qin (Jane) He Anne‐Liv Schulz Stephen Yates Victor Biton
Pages: 636-646
Effectiveness and tolerability of lacosamide as add‐on therapy in patients with brain tumor–related epilepsy: Results from a prospective, noninterventional study in European clinical practice (VIBES)
Roberta Rudà Caroline Houillier Marta Maschio Jaap C. Reijneveld Scarlett Hellot Marc De Backer Jane Chan Lars Joeres Iryna Leunikava Martin Glas Robin Grant
Pages: 647-656
Testing association of rare genetic variants with resistance to three common antiseizure medications
Stefan Wolking Claudia Moreau Anne T. Nies Elke Schaeffeler Mark McCormack Pauls Auce Andreja Avbersek Felicitas Becker Martin Krenn Rikke S. Møller Marina Nikanorova Yvonne G. Weber Sarah Weckhuysen Gianpiero L. Cavalleri Norman Delanty Chantal
Pages: 657-666
Somatic variants in new candidate genes identified in focal cortical dysplasia type II
Zhongbin Zhang Kai Gao Qingzhu Liu Jiapeng Zhou Xiyuan Li Na Lang Ming Liu Tianshuang Wang Jie Zhang Hui Wang Ying Dong Taoyun Ji Shuang Wang Xiaoyan Liu Yuwu Jiang Lixin Cai Ye Wu
Pages: 667-678
KCNT1‐related epilepsy: An international multicenter cohort of 27 pediatric cases
Felippe Borlot Ahmed Abushama Nadine Morrison‐Levy Puneet Jain Kollencheri Puthenveettil Vinayan Musaad Abukhalid Hesham M. Aldhalaan Hanin S. Almuzaini Sheffali Gulati Tova Hershkovitz Ramesh Konanki Lokesh Lingappa Aimee F. Luat Shatha
Pages: 679-692
Posttraumatic epilepsy in intensive care unit–treated pediatric traumatic brain injury patients
Era D. Mikkonen Markus B. Skrifvars Matti Reinikainen Stepani Bendel Ruut Laitio Sanna Hoppu Tero Ala‐Kokko Atte Karppinen Rahul Raj
Pages: 693-701
Mortality in infantile spasms: A hospital‐based study
Chellamani Harini Elanagan Nagarajan Ann M. Bergin Phillip Pearl Tobias Loddenkemper Masanori Takeoka Peter F. Morrison David Coulter Gita Harappanahally Candice Marti Kanwaljit Singh Christopher Yuskaitis Annapurna Poduri Mark H. Libenson
Pages: 702-713
The mortality burden attributable to nontrauma fracture for privately insured adults with epilepsy
Daniel G. Whitney Sarah Bell Nancy A. McNamara Edward A. Hurvitz
Pages: 714-724
Effects of hippocampus‐sparing resections in the temporal lobe: Hippocampal atrophy is associated with a decline in memory performance
Kathrin Wagner Karin Gau Birgitta Metternich Maximilian J. Geiger Anne‐Sophie Wendling Navah E. Kadish Gitta Reuner Hans Mayer Irina Mader Jürgen Beck Josef Zentner Horst Urbach Andreas Schulze‐Bonhage Christoph P. Kaller Niels A. Foit
Pages: 725-734
Shared hippocampal abnormalities in sporadic temporal lobe epilepsy patients and their siblings
Lili Long Marian Galovic Yayu Chen Tjardo Postma Sjoerd B. Vos Fenglai Xiao Wenyue Wu Yanmin Song Sha Huang Matthias Koepp Bo Xiao
Pages: 735-746
The understanding of mental states and the cognitive phenotype of frontal lobe epilepsy
Anna Rita Giovagnoli Giulia Maria Tallarita Annalisa Parente Chiara Pastori Marco de Curtis
Pages: 747-757
Peri‐ictal responsiveness to the social environment is greater in psychogenic nonepileptic than epileptic seizures
Alistair Wardrope Siew Wong Jonathan McLaughlan Maytal Wolfe Maria Oto Markus Reuber
Pages: 758-765
Visual seizure annotation and automated seizure detection using behind‐the‐ear electroencephalographic channels
Kaat Vandecasteele Thomas De Cooman Jonathan Dan Evy Cleeren Sabine Van Huffel Borbála Hunyadi Wim Van Paesschen
Pages: 766-775
Forecasting cycles of seizure likelihood
Philippa J. Karoly Mark J. Cook Matias Maturana Ewan S. Nurse Daniel Payne Benjamin H. Brinkmann David B. Grayden Sonya B. Dumanis Mark P. Richardson Greg A. Worrell Andreas Schulze‐Bonhage Levin Kuhlmann Dean R. Freestone
Pages: 776-786
Adenosine kinase and adenosine receptors A1R and A2AR in temporal lobe epilepsy and hippocampal sclerosis and association with risk factors for SUDEP
Smriti Patodia Beatrice Paradiso Maria Garcia Matthew Ellis Beate Diehl Maria Thom Orrin Devinsky
Pages: 787-797
Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval
John G. R. Jefferys Alexander Ashby‐Lumsden Thelma A. Lovick
Pages: 798-809
Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized Caenorhabditis elegans
Bangfu Zhu Jennifer C. H. Mak Andrew P. Morris Anthony G. Marson Jeff W. Barclay Graeme J. Sills Alan Morgan
Pages: 810-821
Inherited RORB pathogenic variants: Overlap of photosensitive genetic generalized and occipital lobe epilepsy
Lynette G. Sadleir Guillem de Valles‐Ibáñez Chontelle King Matthew Coleman Stuart Mossman Sarah Paterson John Nguyen Samuel F. Berkovic Saul Mullen Melanie Bahlo Michael S. Hildebrand Heather C. Mefford Ingrid E. Scheffer
Pages: e23-e29
Focal and generalized seizure activity after local hippocampal or cortical ablation of NaV1.1 channels in mice
Nico A. Jansen Anisa Dehghani Cor Breukel Else A. Tolner Arn M. J. M. van den Maagdenberg
Pages: e30-e36
Epilepsia: Volumen 61, Issue 3, Marzo 2020
Biological concepts in human sodium channel epilepsies and their relevance in clinical practice
Andreas Brunklaus Juanjiangmeng Du Felix Steckler Ismael I. Ghanty Katrine M. Johannesen Christina Dühring Fenger Stephanie Schorge David Baez‐Nieto Hao‐Ran Wang Andrew Allen Jen Q. Pan Holger Lerche Henrike Heyne Joseph D.
Pages: 387-399
Exacerbation of hepatic cirrhosis may trigger admission for epilepsy and status epilepticus
Jonathan M. Gursky Kyle C. Rossi Nathalie Jetté Mandip S. Dhamoon
Pages: 400-407
Mesial temporal resection following long‐term ambulatory intracranial EEG monitoring with a direct brain‐responsive neurostimulation system
Lawrence J. Hirsch Emily A. Mirro Vicenta Salanova Thomas C. Witt Cornelia N. Drees Mesha‐Gay Brown Ricky W. Lee Toni L. Sadler Elizabeth A. Felton Paul Rutecki Hae Won Shin Eldad Hadar Manu Hegde Vikram R. Rao Lilit Mnatsakanyan Deepak S. Madhavan Tarek J. Zakaria Anli A. Liu Christianne N. Heck Janet E. Greenwood Jeffrey K. Bigelow Dileep R. Nair Andreas V. Alexopoulos Michael Mackow Jonathan C. Edwards Nadia Sotudeh Ruben I. Kuzniecky Ryder P. Gwinn Michael J. Doherty Eric B. Geller Martha J. Morrell
Pages: 408-420
Same same but different: A Web‐based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations
Joshua Kubach Angelika Muhlebner‐Fahrngruber Figen Soylemezoglu Hajime Miyata Pitt Niehusmann Mrinalini Honavar Fabio Rogerio Se‐Hoon Kim Eleonora Aronica Rita Garbelli Samuel Vilz Alexander Popp Stefan Walcher Christoph Neuner Michael Scholz Stefanie Kuerten Verena Schropp Sebastian Roeder Philip Eichhorn Markus Eckstein Axel Brehmer Katja Kobow Roland Coras Ingmar Blumcke Samir Jabari
Pages: 421-432
MRI profiling of focal cortical dysplasia using multi‐compartment diffusion models
Sara Lorio Sophie Adler Roxana Gunny Felice D’Arco Enrico Kaden Konrad Wagstyl Thomas S. Jacques Chris A. Clark Judith Helen Cross Torsten Baldeweg David W. Carmichael
Pages: 433-444
Treatment initiation decisions in newly diagnosed epilepsy–A longitudinal cohort study
Sameer Sharma Zhibin Chen Maria Rychkova John Dunne Judy Lee Linda Kalilani Nicholas Lawn Patrick Kwan
Pages: 445-454
Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers
R. Edward Hogan Barry E. Gidal Barry Koplowitz Luana P. Koplowitz Richard E. Lowenthal Enrique Carrazana
Pages: 455-464
Long‐term outcomes of reoperations in epilepsy surgery
Ruta Yardi Marcia E. Morita‐Sherman Zachary Fitzgerald Vineet Punia James Bena Shannon Morrison Imad Najm William Bingaman Lara Jehi
Pages: 465-478
Accidental deaths in young people with epilepsy and psychiatric comorbidity—A Danish nationwide cohort study
Sissel K. Aagaard Julie W. Dreier Yuelian Sun Thomas M. Laursen Jakob Christensen
Pages: 479-488
Predictors of focal to bilateral tonic‐clonic seizures during long‐term video‐EEG monitoring
Max C. Pensel Martin Schnuerch Christian E. Elger Rainer Surges
Pages: 489-497
Development of a model to predict electroencephalographic seizures in critically ill children
France W. Fung Marin Jacobwitz Darshana S. Parikh Lisa Vala Maureen Donnelly Jiaxin Fan Rui Xiao Alexis A. Topjian Nicholas S. Abend
Pages: 498-508
Early epilepsy in children with Zika‐related microcephaly in a cohort in Recife, Brazil: Characteristics, electroencephalographic findings, and treatment response
Maria Durce C. G. Carvalho Ricardo A. A. Ximenes Ulisses R. Montarroyos Paula F. S. da Silva Luciana P. A. Andrade‐Valença Sophie H. Eickmann Regina C. Ramos Maria Ângela W. Rocha Thalia V. B. de Araujo Maria de Fátima P. M. de Albuquerque Celina M. T. Martelli Wayner V. de Souza Elizabeth B. Brickley Demócrito de B. Miranda‐Filho on behalf of the Microcephaly Epidemic Research Group
Pages: 509-518
Mortality and morbidity of patients with treated and untreated epilepsy in New Zealand
Kristen Joy Hamilton Zhibin Chen Andrew Tomlin Patrick Kwan
Pages: 519-527
Quantitative readability analysis of websites providing information on traumatic brain injury and epilepsy: A need for clear communication
Daniel José Correa Lindsey Milano Churl‐Su Kwon Nathalie Jetté Dennis Dlugos Lauren Harte‐Hargrove Mary Jo Pugh Jessica K. Smith Solomon L. Moshé
Pages: 528-538
Positive illusions determine quality of life in drug‐resistant epilepsy
Sarah J. Wilson Genevieve Rayner Jessamae Pieters
Pages: 539-548
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome
Ettore Tiraboschi Silvia Martina Wietske van der Ent Kamil Grzyb Kinga Gawel Maria Lorena Cordero‐Maldonado Suresh Kumar Poovathingal Sarah Heintz Somisetty Venkata Satheesh Jarle Brattespe Ju Xu Maximiliano Suster Alexander Skupin Camila V. Esguerra
Pages: 549-560
Optogenetic intervention of seizures improves spatial memory in a mouse model of chronic temporal lobe epilepsy
Hannah K. Kim Tilo Gschwind Theresa M. Nguyen Anh D. Bui Sylwia Felong Kristen Ampig David Suh Annie V. Ciernia Marcelo A. Wood Ivan Soltesz
Pages: 561-571
Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin
Shruthi H. Iyer Ankita Aggarwal Ted J. Warren Jodi Hallgren Peter W. Abel Timothy A. Simeone Kristina A. Simeone
Pages: 572-588
SUDEP among young adults in the San Diego County Medical Examiner Office
Esma Karlovich Orrin Devinsky Michael Brandsoy Daniel Friedman
Pages: e17-e22
Epilepsia: Volumen 61, Issue 2, Febrero 2020
Impaired vigilance networks in temporal lobe epilepsy: Mechanisms and clinical implications
Dario J. Englot Victoria L. Morgan Catie Chang
Pages: 189-202
Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity
Peravina Therajaran John A. Hamilton Terence J. O'Brien Nigel C. Jones Idrish Ali
Pages: 203-215
Trends in pediatric epilepsy surgery in Europe between 2008 and 2015: Country‐, center‐, and age‐specific variation
Carmen Barba Judith Helen Cross Kees Braun Massimo Cossu Kerstin Alexandra Klotz Salvatore De Masi Maria Angeles Perez Jiménez Eija Gaily Nicola Specchio Pedro Cabral Joseph Toulouse Petia Dimova Domenica Battaglia Elena Freri Alessandro Consales
Pages: 216-227
Epilepsy‐specific patient‐reported outcome measures of children's health‐related quality of life: A systematic review of measurement properties
Holly Crudgington Morwenna Rogers Hannah Morris Paul Gringras Deb K. Pal Christopher Morris
Pages: 230-248
Genetic diagnoses in epilepsy: The impact of dynamic exome analysis in a pediatric cohort
Anne Rochtus Heather E. Olson Lacey Smith Louisa G. Keith Christelle El Achkar Alan Taylor Sonal Mahida Meredith Park McKenna Kelly Catherine Shain Shira Rockowitz Beth Rosen Sheidley Annapurna Poduri
Pages: 249-258
Hyperlipidemia in patients newly treated with anticonvulsants: A population study
Scott Mintzer Misung Yi Sarah Hegarty Vittorio Maio Scott Keith
Pages: 259-266
A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects
Julie Crockett David Critchley Bola Tayo Joris Berwaerts Gilmour Morrison
Pages: 267-277
Efficacy and safety of adjunctive perampanel 4 mg/d for the treatment of focal seizures: A pooled post hoc analysis of four randomized, double‐blind, phase III studies
Bernhard J. Steinhoff Anna Patten Betsy Williams Manoj Malhotra
Pages: 278-286
Seven‐tesla susceptibility‐weighted analysis of hippocampal venous structures: Application to magnetic‐resonance–normal focal epilepsy
Rebecca Emily Feldman Lara Vanessa Marcuse Gaurav Verma Stephanie Sian Gabriella Brown Alexandru Rus John Watson Rutland Bradley Neil Delman Priti Balchandani Madeline Cara Fields
Pages: 287-296
Hippocampal profiling: Localized magnetic resonance imaging volumetry and T2 relaxometry for hippocampal sclerosis
Sjoerd B. Vos Gavin P. Winston Olivia Goodkin Hugh G. Pemberton Frederik Barkhof Ferran Prados Marian Galovic Matthias Koepp Sebastien Ourselin M. Jorge Cardoso John S. Duncan
Pages: 297-309
Neuropeptide depletion in the amygdala in sudden unexpected death in epilepsy: A postmortem study
Alyma Somani Charlotte Perry Smriti Patodia Zuzanna Michalak Matthew Ellis Sanjay M. Sisodiya Maria Thom
Pages: 310-318
The economic burden of caregiving in epilepsy: An estimate based on a survey of US caregivers
Shaun A. Hussain Jesse D. Ortendahl Tanya G. K. Bentley Amanda L. Harmon Shaloo Gupta Charles E. Begley Ibrahim Khilfeh Russell L. Knoth
Pages: 319-329
Phase‐dependent modulation of cortical and thalamic sensory responses during spike‐and‐wave discharges
Mark S. Williams Sarah Lecas Stéphane Charpier Séverine Mahon
Pages: 330-341
Audiogenic seizure as a model of sudden death in epilepsy: A comparative study between four inbred mouse strains from early life to adulthood
Benoît Martin Gabriel Dieuset Jodi L. Pawluski Nathalie Costet Arnaud Biraben
Pages: 342-349
Ensembling crowdsourced seizure prediction algorithms using long‐term human intracranial EEG
Chip Reuben Philippa Karoly Dean R. Freestone Andriy Temko Alexandre Barachant Feng Li Gilberto Titericz Jr. Brian W. Lang Daniel Lavery Kelly Roman Derek Broadhead Gareth Jones Qingnan Tang Irina Ivanenko Oleg Panichev Timothée Proix Michal Náhlík Daniel B. Grunberg David B. Grayden Mark J. Cook Levin Kuhlmann
Pages: e7-e12
Seizures induce obstructive apnea in DBA/2J audiogenic seizure‐prone mice: Lifesaving impact of tracheal implants
Rachel Irizarry Daniel Sukato Richard Kollmar Samuel Schild Joshua Silverman Krishnamurthi Sundaram Stacy Stephenson Mark Stewart
Pages: e13-e16
Epilepsia: Volumen 61, Issue 1, Enero 2020
Cerebrospinal fluid and blood biomarkers of status epilepticus
Aurélie Hanin Virginie Lambrecq Jérôme Alexandre Denis Françoise Imbert‐Bismut Benoît Rucheton Foudil Lamari Dominique Bonnefont‐Rousselot Sophie Demeret Vincent Navarro
Pages: 6-18 First Published: 11 December 2019
Realistic driving simulation during generalized epileptiform discharges to identify electroencephalographic features related to motor vehicle safety: Feasibility and pilot study
Eli Cohen Prince Antwi Barbara C. Banz Peter Vincent Rick Saha Christopher A. Arencibia Jun H. Ryu Ece Atac Nehan Saleem Shiori Tomatsu Kohleman Swift Claire Hu Heinz Krestel Pue Farooque Susan Levy Jia Wu Michael Crowley Federico E. Vaca Hal Blumenfeld
Pages: 19-28 First Published: 24 October 2019
Prospective validation study of an epilepsy seizure risk system for outpatient evaluation
Sharon Chiang Daniel M. Goldenholz Robert Moss Vikram R. Rao Zulfi Haneef William H. Theodore Jonathan K. Kleen Jay Gavvala Marina Vannucci John M. Stern
Pages: 29-38 First Published: 02 December 2019
Prospective validation of a machine learning model that uses provider notes to identify candidates for resective epilepsy surgery
Benjamin D. Wissel Hansel M. Greiner Tracy A. Glauser Katherine D. Holland‐Bouley Francesco T. Mangano Daniel Santel Robert Faist Nanhua Zhang John P. Pestian Rhonda D. Szczesniak Judith W. Dexheimer
Pages: 39-48 First Published: 29 November 2019
Clinical benefit of presurgical EEG‐fMRI in difficult‐to‐localize focal epilepsy: A single‐institution retrospective review
Magdalena A. Kowalczyk Amir Omidvarnia David F. Abbott Chris Tailby David N. Vaughan Graeme D. Jackson
Pages: 49-60 First Published: 02 December 2019
Readmission after neurosurgical intervention in epilepsy: A nationwide cohort analysis
Churl‐Su Kwon Parul Agarwal Varsha Subramaniam Mandip Dhamoon Madhu Mazumdar Anusha Yeshokumar Fedor Panov Saadi Ghatan Nathalie Jetté
Pages: 61-69 First Published: 02 December 2019
Volume change in amygdala enlargement as a prognostic factor in patients with temporal lobe epilepsy: A longitudinal study
Han Kyu Na Ho‐Joon Lee Seok‐Jun Hong Dong Hyun Lee Kyung Min Kim Hyung Woo Lee Kyoung Heo Kyoo Ho Cho
Pages: 70-80 First Published: 11 December 2019
Epileptogenicity in tuberous sclerosis complex: A stereoelectroencephalographic study
Andrew Neal Karine Ostrowsky‐Coste Julien Jung Stanislas Lagarde Louis Maillard Philippe Kahane Renaud Touraine Helene Catenoix Alexandra Montavont Jean Isnard Alexis Arzimanoglou Fabrice Bartolomei Marc Guenot Sylvain Rheims
Pages: 81-95 First Published: 20 December 2019
Responsive neurostimulation for regional neocortical epilepsy
Brandy B. Ma Madeline C. Fields Robert C. Knowlton Edward F. Chang Jerzy P. Szaflarski Lara V. Marcuse Vikram R. Rao
Pages: 96-106 First Published: 11 December 2019
Doing without valproate in women of childbearing potential with idiopathic generalized epilepsy: Implications on seizure outcome
Emanuele Cerulli Irelli Alessandra Morano Enrico Cocchi Sara Casciato Martina Fanella Mariarita Albini Federica Avorio Luca M. Basili Giacomo Fisco Francesca A. Barone Addolarata Mascia Alfredo D’Aniello Mario Manfredi Jinane Fattouch Pierpaolo Quarato Anna Teresa Giallonardo Giancarlo Di Gennaro Carlo Di Bonaventura
Pages: 107-114 First Published: 11 December 2019
External validation and comparison of two prediction models for seizure recurrence after the withdrawal of antiepileptic drugs in adult patients
Jiahe Lin Siqi Ding Xueying Li Yingjie Hua Xinshi Wang Ruqian He Yanru Du Niange Xia Yanyan Chen Zhenguo Zhu Rongyuan Zheng Huiqin Xu
Pages: 115-124 First Published: 02 December 2019
Open‐label study to investigate the safety and efficacy of adjunctive perampanel in pediatric patients (4 to <12 years) with inadequately controlled focal seizures or generalized tonic‐clonic seizures
Andras Fogarasi Robert Flamini Mathieu Milh Steven Phillips Shinsaku Yoshitomi Anna Patten Takao Takase Antonio Laurenza Leock Y. Ngo
Pages: 125-137 First Published: 07 January 2020
Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs
Imran H. Quraishi Michael R. Mercier Tara L. Skarpaas Lawrence J. Hirsch
Pages: 138-148 First Published: 17 December 2019
Pharmacokinetic and pharmacodynamic analysis of (2S,3S)‐sec‐butylpropylacetamide (SPD) in rats and pigs—A CNS‐active stereoisomer of SPD
David Bibi Meir Bialer
Pages: 149-156 First Published: 20 January 2020
A face‐to‐face comparison of the intra‐amygdala and intrahippocampal kainate mouse models of mesial temporal lobe epilepsy and their utility for testing novel therapies
Lisa Welzel Alina Schidlitzki Friederike Twele Muneeb Anjum Wolfgang Löscher
Pages: 157-170 First Published: 11 December 2019
Oligodendrocyte lineage and myelination are compromised in the gray matter of focal cortical dysplasia type IIa
Catharina Donkels Myriam Peters Mateo T. Fariña Núñez Julia M. Nakagawa Matthias Kirsch Andreas Vlachos Christian Scheiwe Andreas Schulze‐Bonhage Marco Prinz Jürgen Beck Carola A. Haas
Pages: 171-184 First Published: 24 December 2019